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Akinori Iwashita Selected Research

5- chloro- 2- (3- (4- phenyl- 3,6- dihydro- 1(2H)- pyridinyl)propyl)- 4(3H)- quinazolinone

8/2004A novel and potent poly(ADP-ribose) polymerase-1 inhibitor, FR247304 (5-chloro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazolinone), attenuates neuronal damage in in vitro and in vivo models of cerebral ischemia.

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Akinori Iwashita Research Topics

Disease

7Neoplasms (Cancer)
03/2020 - 05/2002
5Parkinson Disease (Parkinson's Disease)
12/2008 - 06/2004
5Neurodegenerative Diseases (Neurodegenerative Disease)
03/2007 - 12/2003
3Stroke (Strokes)
03/2007 - 12/2003
3Brain Ischemia (Cerebral Ischemia)
03/2007 - 12/2003
3Brain Injuries (Brain Injury)
03/2007 - 12/2003
2Polyps
07/2021 - 01/2016
2Glandular and Epithelial Neoplasms (Neoplasms, Glandular)
04/2016 - 08/2015
2Colorectal Neoplasms (Colorectal Cancer)
01/2014 - 01/2009
2Ulcerative Colitis
10/2011 - 10/2003
2Crohn Disease (Crohn's Disease)
07/2011 - 01/2003
2Adenocarcinoma
05/2010 - 11/2003
2Catalepsy
07/2008 - 11/2007
2Memory Disorders (Memory Loss)
11/2007 - 09/2004
2Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
03/2007 - 08/2004
2Lymphatic Metastasis
11/2003 - 11/2003
2Carcinoma (Carcinomatosis)
11/2003 - 08/2002
1AIDS-Related Complex (ARC)
02/2018
1Ascites
01/2017
1Adenoma (Adenomas)
08/2015
1Edema (Dropsy)
10/2011
1Ulcer
10/2011
1Cryptococcosis
07/2011
1Metaplasia
03/2011
1Pouchitis
10/2010
1Arthritis (Polyarthritis)
09/2010
1Hyperalgesia
09/2010
1Osteoarthritis
09/2010
1Pain (Aches)
09/2010
1Ataxia (Dyssynergia)
12/2008
1Vomiting
12/2008
1Neuroblastoma
06/2007
1Marginal Zone B-Cell Lymphoma (MALT Lymphoma)
08/2005
1Lymphoma (Lymphomas)
08/2005

Drug/Important Bio-Agent (IBA)

4Neuroprotective AgentsIBA
06/2007 - 12/2003
3Adenosine A2A Receptor (Adenosine A2A Receptors)IBA
12/2008 - 11/2007
3Adenosine (Adenocard)FDA LinkGeneric
12/2008 - 11/2007
3Pharmaceutical PreparationsIBA
12/2008 - 02/2003
31- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
12/2008 - 06/2004
35- (5- amino- 3- (4- fluorophenyl)pyrazin- 2- yl)- 1- isopropylprydine- 2(1H)- oneIBA
12/2008 - 11/2007
2Perilipin-2IBA
07/2021 - 01/2016
2Indicators and Reagents (Reagents)IBA
03/2020 - 11/2003
2Tumor Biomarkers (Tumor Markers)IBA
01/2017 - 07/2013
2LipidsIBA
04/2016 - 08/2015
2Haloperidol (Haldol)FDA LinkGeneric
07/2008 - 11/2007
2Scopolamine (Hyoscine)FDA Link
11/2007 - 09/2004
2Reactive Oxygen Species (Oxygen Radicals)IBA
08/2004 - 12/2003
2Poly (ADP-Ribose) Polymerase-1IBA
08/2004 - 06/2004
2QuinazolinonesIBA
08/2004 - 06/2004
1Indigo Carmine (Indigo Blue)IBA
02/2018
1Triglycerides (Triacylglycerol)IBA
04/2016
1Sterol Regulatory Element Binding Protein 1IBA
04/2016
1Carnitine O-Palmitoyltransferase (Carnitine Palmitoyltransferase II)IBA
04/2016
1ApolipoproteinsIBA
04/2016
1Fatty Acids (Saturated Fatty Acids)IBA
04/2016
1Sterol O-AcyltransferaseIBA
04/2016
1Coenzyme A (CoA)IBA
04/2016
1microsomal triglyceride transfer proteinIBA
04/2016
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
04/2016
1Lipoproteins (Lipoprotein)IBA
04/2016
1Fatty Acid-Binding ProteinsIBA
04/2016
1Oxidoreductases (Dehydrogenase)IBA
04/2016
1Acyl Coenzyme A (Acyl CoA)IBA
04/2016
1Lipase (Acid Lipase)FDA Link
04/2016
1Diacylglycerol O-AcyltransferaseIBA
04/2016
1FatsIBA
08/2015
1Capsules (Microcapsules)IBA
10/2011
1Infliximab (Remicade)FDA Link
07/2011
1HemosiderinIBA
03/2011
1rho-Associated KinasesIBA
09/2010
11- (2- hydroxy- 1- phenylethyl)- 3- (4- (pyridin- 4- yl)phenyl)ureaIBA
09/2010
1Analgesics (Analgesic Drugs)IBA
09/2010
1Proteins (Proteins, Gene)FDA Link
09/2010
1Urea (Carbamide)FDA LinkGeneric
09/2010
1Pepsinogen A (Pepsinogen)IBA
05/2010
1doxifluridineIBA
01/2009
1Amantadine (Aman)FDA LinkGeneric
12/2008
1Selegiline (E250)FDA LinkGeneric
12/2008
1Bromocriptine (Parlodel)FDA LinkGeneric
12/2008
1P-2 (P 2)IBA
11/2007
1istradefyllineIBA
11/2007
1Dopamine (Intropin)FDA LinkGeneric
11/2007
1Dihydroxyphenylalanine (Dopa)IBA
11/2007
1Adenosine-5'-(N-ethylcarboxamide) (NECA)IBA
11/2007
1Levodopa (L Dopa)FDA LinkGeneric
11/2007
1ThapsigarginIBA
06/2007
14- (3- (2- propyl- 3- hydroxy- 4- acetyl)phenoxy)propyloxyphenoxy acetic acidIBA
03/2007
1PPAR deltaIBA
03/2007
1Cytotoxins (Cytolysins)IBA
03/2007
1GW 501516IBA
03/2007
1Acetic Acid (Vinegar)FDA LinkGeneric
03/2007
1Phenobarbital (Luminal)FDA Link
08/2005
1Anti-Bacterial Agents (Antibiotics)IBA
08/2005
12- (4- chlorophenyl)- 5- quinoxalinecarboxamideIBA
09/2004
12- (1- methyl- 4- piperidinyl)- 6- (2- phenylpyrazolo(1,5- a)pyridin- 3- yl)- 3(2H)- pyridazinoneIBA
09/2004

Therapy/Procedure

2Restorative Proctocolectomy
10/2011 - 10/2010
1Lasers (Laser)
01/2014
1Adjuvant Chemotherapy
01/2009
1Intramuscular Injections
07/2008
1Therapeutics
08/2005